Work Packages
WP1 | Isolation and Characterization of AHR Genes
The project will collect and study AHR gene sequences in Mytilus galloprovincialis to understand their role in bivalve detoxification
WP3 | In vivo testing
Selected compounds will be tested in live bivalves to evaluate their effect on xenobiotic detoxification mechanisms
WP5 | Assessing Model Versatility
The project will explore the applicability of the protocol across different bivalve species and types of biotoxins, aiming for a versatile solution
WP2 | Screening Natural Compounds
InnovBivalves will identify natural compounds capable of activating AHR and NR1J1 receptors, which may enhance bivalve detoxification
WP4 | Proof-of-Concept Protocol
The project will develop a pilot depuration protocol using identified compounds, testing efficiency and potential application in contaminated bivalves